Phillips Lab at UCSF

Publications

The following includes a selection of recent publications from our lab. View the complete list here on PubMed.

 

SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis

Singer MS, Phillips JJ, Lemjabbar-Alaoui H, Wang YQ, Wu J, Goldman R, Rosen SD.

Clin Chim Acta. 2015 Feb 2; 440: 72-8. doi: 10.1016/j.cca.2014.10.038. Epub 2014 Oct 31.
PubMed Link >

Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas

Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA, Costello JF.

Neuro Oncol. 2018 Apr 9; 20 (5): 632-641. doi: 10.1093/neuonc/nox205.
PubMed Link >

Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia

Vatsavayai SC, Yoon SJ, Gardner RC, Gendron TF, Vargas JN, Trujillo A, Pribadi M, Phillips JJ, Gaus SE, Hixson JD, Garcia PA, Rabinovici GD, Coppola G, Geschwind DH, Petrucelli L, Miller BL, Seeley WW.

Brain. 2016; 139 (Pt 12): 3202-3216. Epub 2016 Oct 22.
PubMed Link >

The genetic landscape of gliomas arising after therapeutic radiation

López GY, Van Ziffle J, Onodera C, Grenert JP, Yeh I, Bastian BC, Clarke J, Oberheim Bush NA, Taylor J, Chang S, Butowski N, Banerjee A, Mueller S, Kline C, Torkildson J, Samuel D, Siongco A, Raffel C, Gupta N, Kunwar S, Mummaneni P, Aghi M, Theodosopoulos P, Berger M, Phillips JJ, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA.

Acta Neuropathol. 2019; 137 (1): 139-150. doi: 10.1007/s00401-018-1906-z. Epub 2018 Sep 8.
PubMed Link >

Glycosylation alterations in lung and brain cancer

Lemjabbar-Alaoui H, McKinney A, Yang YW, Tran VM, Phillips JJ.

Adv Cancer Res. 2015 Feb 7; 126: 305-44. doi: 10.1016/bs.acr.2014.11.007. Epub 2015 Feb 7. Review.
PubMed Link >

Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma

Byron SA, Tran NL, Halperin RF, Phillips JJ, Kuhn JG, de Groot JF, Colman H, Ligon KL, Wen PY, Cloughesy TF, Mellinghoff IK, Butowski NA, Taylor JW, Clarke JL, Chang SM, Berger MS, Molinaro AM, Maggiora GM, Peng S, Nasser S, Liang WS, Trent JM, Berens ME, Carpten JD, Craig DW, Prados MD.

Clin Cancer Res. 2018 Nov 5; 24 (2): 295-305. doi: 10.1158/1078-0432.CCR-17-0963. Epub 2017 Oct 26.
PubMed Link >

Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation

Phillips JJ, Gong H, Chen K, Joseph NM, van Ziffle J, Jin LW, Bastian BC, Bollen AW, Perry A, Nicolaides T, Solomon DA, Shieh JT.

Acta Neuropathol. 2016; 132 (5): 757-760. Epub 2016 Sep 13.
PubMed Link >

Phase-2 trial of palbociclib in adult patients with recurrent RB1-positive glioblastoma

Taylor JW, Parikh M, Phillips JJ, James CD, Molinaro AM, Butowski NA, Clarke JL, Oberheim-Bush NA, Chang SM, Berger MS, Prados M.

J Neurooncol. 2018; 140 (2): 477-483. doi: 10.1007/s11060-018-2977-3. Epub 2018 Aug 27.
PubMed Link >

IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism

Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM.

Cancer Res. 2015 Aug 1; 75 (15): 2999-3009. doi: 10.1158/0008-5472.CAN-15-0840. Epub 2015 Jun 4.
PubMed Link >

Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression

Lopez GY, Oberheim Bush NA, Phillips JJ, Bouffard JP, Moshel YA, Jaeckle K, Kleinschmidt-DeMasters BK, Rosenblum MK, Perry A, Solomon DA.

Acta Neuropathol. 2017; 134 (6): 961-963. doi: 10.1007/s00401-017-1780-0. Epub 2017 Oct 23.
PubMed Link >

Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma

Han SJ, Reis G, Kohanbash G, Shrivastav S, Magill ST, Molinaro AM, McDermott MW, Theodosopoulos PV, Aghi MK, Berger MS, Butowski NA, Barani I, Phillips JJ, Perry A, Okada H.

J Neurooncol. 2016; 130 (3): 543-552. Epub 2016 Sep 13.
PubMed Link >

An oncolytic measles virus-sensitive Group 3 medulloblastoma model in immune-competent mice

Lal S, Carrera D, Phillips JJ, Weiss WA, Raffel C.

Neuro Oncol. 2018 Nov 12; 20 (12): 1606-1615. doi: 10.1093/neuonc/noy089.
PubMed Link >

Pro-angiogenic cellular and genomic expression patterns within glioblastoma influences dynamic susceptibility weighted perfusion MRI

Barajas RF Jr, Phillips JJ, Vandenberg SR, McDermott MW, Berger MS, Dillon WP, Cha S.

Clin Radiol. 2015; 70 (10): 1087-95. doi: 10.1016/j.crad.2015.03.006. Epub 2015 Jul 29.
PubMed Link >

Protein Analysis of Glioblastoma Primary and Posttreatment Pairs Suggests a Mesenchymal Shift at Recurrence

Wood MD, Reis GF, Reuss DE, Phillips JJ.

J Neuropathol Exp Neurol. 2016; 75 (10): 925-935. Epub 2016 Aug 18.
PubMed Link >

Relationship of In Vivo MR Parameters to Histopathological and Molecular Characteristics of Newly Diagnosed, Nonenhancing Lower-Grade Gliomas

Luks TL, McKnight TR, Jalbert LE, Williams A, Neill E, Lobo KA, Persson AI, Perry A, Phillips JJ, Molinaro AM, Chang SM, Nelson SJ.

Transl Oncol. 2018; 11 (4): 941-949. doi: 10.1016/j.tranon.2018.05.005. Epub 2018 Jun 18.
PubMed Link >